Our Studies
In vivo EfficacyStudies

In vivo efficacy studies is the study of the biological effects of a drug in a complex living organism and is used to observe the complex physiological effects of a drug. Our scientist working on early research and proof-of-concept (POC) pharmacological studies in relevant animal models of human diseases to efficacy evaluations. Our scientific team has wide experience with numerous disease models and assays, as well as efficient in developing new models to meet the specific needs of a particular compound or discovery program. We have established various models to evaluate the efficacy of target molecule in various pain, inflammation, neuropharmacological studies, wound healing and metabolic disorders, etc. Which includes:

PAIN

Neuropathic pain

• Diabetic neuropathy
• Chronic Constriction Injury
• Spinal Nerve Ligation
• Spared Nerve Injury
• Sciatic Nerve Ligation

Inflammatory pain

• Formalin-induced Pain (Acute)
• Freund's Adjuvant-induced Hyperalgesia (Chronic)
• Carrageenan-induced Hyperalgesia
• MIA/MMT-induced OA

Mechanical & Thermal Nociception

• Rat Pinch Model
• Tail Flick
• Hot plate

Visceral pain

• Acetic Acid-induced Writhing